The main contributing factors to the development of psoriatic arthritis are genetics, immunological factors and the environment. Psoriatic nail dsytrophy: thickening and ridging of the nails with separation of the nail from the underlying nail bed. Joint symptoms may flare with a flare in skin psoriasis but quite commonly the skin symptoms behave independently of joint symptoms. Clinical Symptoms of Skin, Nails, and Joints Manifest Independently in Patients with Concomitant Psoriasis and Psoriatic Arthritis. About one quarter of patients with Pso also develop psoriatic arthritis (PsA) 2. The autoimmune disease psoriasis can often make a person’s life painful and difficult. 5 million Americans living with the disease, which presents as an unsightly build-up of dead skin cells on the skin, and in the nails and joints. While they can occur independently, patients who develop them generally have plaque psoriasis.
Psoriatic arthritis is marked by joint pain, toe and finger swelling, nail pitting, and conjunctivitis. Patients with psoriatic arthritis can develop inflammation of tendons, cartilage, eyes, lung lining, and, rarely, the aorta. The arthritis of psoriatic arthritis is treated independently of the psoriasis, with exercise, ice applications, medications, and surgery. Plaque psoriasis can appear on any skin surface, although the knees, elbows, scalp, trunk and nails are the most common locations. An independent expert panel, blinded regarding treatment versus control, found that at 180 days, 85 of the eligible treated toenails were improved by clear nail linear extent (p 0. Janssen Research & Development, LLC. The PASI produces a numeric score that can range from 0 to 72. (quadrants) and is graded independently for both nail matrix psoriasis and nail bed psoriasis.
Psoriasis in children and adolescents can have a significant impact on quality of life by interfering with self-esteem, family and social relationships and school and work 7 9. Nail changes can precede, coincide with, or develop after skin psoriasis. Clinical symptoms of skin, nails, and joints manifest independently in patients with concomitant psoriasis and psoriatic arthritis. Only one or two out of every 10 people with psoriasis will develop psoriatic arthritis. In addition, there are Independent Living Centres in each state that provide advice on products and services, including aids and devices, that can help with day-to-day activities.